Dr. Md. Zahidul Islam (Jewel),

- To reveal the mechanism and mode of action of cell-penetrating peptides and antimicrobial peptides on lipid membranes by single GUV method.

Assistant Professor

Dept. of Biotechnology and Genetic Engineering
Jahangirnagar University
Savar, Dhaka-1342

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Dr. Md. Zahidul Islam

Background

Md. Zahidul Islam is currently a Lecturer, Department of Biotechnology and Genetic Engineering, Jahangirnagar University, Savar, Dhaka, Bangladesh. He received his PhD from Shizuoka University, Japan, in 2015. He received his MS and B.Sc. in Biotechnology degree in 2003 and 2001 from Khulna University, Bangladesh. From 2003 to 2012, he worked in Quality Control Department of Medimet Pharmaceuticals Ltd., General pharmaceuticals Ltd., Sanofi-aventis Bangladesh Ltd. (Fisons BD ltd, Hoechst Marion Roussel ltd and Rhone-poulenc Rorer BD Ltd.), and Incepta Vaccine Ltd. He wants to reveal the mechanism or mode of action of cell penetrating peptides on lipid bilayers by the single GUV method.

Selected Publications View All

Research Publications:  I. Journal Papers:
  1. 1

    Md. Zahidul Islam, Sabrina Sharmin, Md. Moniruzzaman, and Masahito Yamazaki (2018), Elementary Processes for the Entry of Cell-Penetrating Peptides into Lipid Bilayer Vesicles and Bacterial Cells, Applied Microbiology and Biotechnology, 102:3879–3892.

  2. 2

    Md. Mizanur Rahman Moghal, Md. Zahidul Islam, Sabrina Sharmin, Victor Levadnyy, Md. Moniruzzaman, Masahito Yamazaki (2018), Continuous Detection of Entry of Cell-Penetrating Peptide Transportan 10 into Single Vesicles, Chemistry and Physics of Lipids, 212, 120–129.

  3. 3

    Md. Zahidul Islam, Sabrina Sharmin, Victor Levadnyy, Sayed Ul Alam Shibly, and Masahito Yamazaki (2017), Effects of Mechanical Properties of Lipid Bilayers on the Entry of Cell-Penetrating Peptides into Single Vesicles, Langmuir, 33, 2433−2443.

  4. 4

    Md. Moniruzzaman, Md. Zahidul Islam, Sabrina Sharmin, Hideo Dohra, and Masahito Yamazaki (2017) Entry of a Six-Residue Antimicrobial Peptide Derived from Lactoferricin B into Single Vesicles and Escherichia coli Cells without Damaging their Membranes, Biochemistry, 56, 4419−4431

  5. 5

    Toshihiko Oka, Moynul Hasan, Md. Zahidul Islam, Md. Moniruzzaman, and Masahito Yamazaki (2017), Low-pH-Induced Lamellar to Bicontinuous Primitive Cubic Phase Transition in Dioleoylphosphatidylserine/Monoolein Membranes, Langmuir, 33, 12487−12496.

  6. 6

    Sabrina Sharmin, Md. Zahidul Islam, Mohammad Abu Sayem Karal, Sayed Ul Alam Shibly, Hideo Dohra and Masahito Yamazaki (2016), Effects of Lipid Composition on the Entry of Cell-Penetrating Peptide Oligoarginine into Single Vesicles, Biochemistry, 55 (30) 4154–4165.

  7. 7

    Sabrina Sharmin, Md. Zahidul Islam, Md. Abdul Jabber (2016) Investigations of medicinal properties of Kalanchoe pinnata under Crassulaceae family, Bioscience and Bioengineering Communication; 2 (3): 130-136.

  8. 8

    Sabrina Sharmin, Zahidul Islam, Md. Abdul Jabber (2016) Isolation and identification of medicinal compounds from Kalanchoe pinnata of Crassulaceae family by 1H NMR. Bioscience and Bioengineering Communication; 2 (2): 123-129.

  9. 9

    Md. Zahidul Islam, Jahangir Md. Alam, Yukihiro Tamba, Mohammad Abu Sayem Karal and Masahito Yamazaki, (2014) The single GUV method for revealing the functions of antimicrobial, pore-forming toxin, and cell-penetrating peptides or proteins, Phys. Chem. Chem. Phys., 16, 15752-15767.

  10. 10

    Zahidul Islam, Hirotaka Ariyama, Jahangir Md. Alam, and Masahito Yamazakia (2014) Entry of cell-penetrating peptide transportan 10 into a single vesicle by translocating across lipid membrane and its induced pores, Biochemistry, 53, 386-396.

  11. 11

    Zahidul Islam, Md. Hasibur Rahman, Fauzia Hafiz. (2009), Cultivation of Oyster Mushroom (Pleurotus flabellatus) on different substrates, International Journal of Sustainable Crop Production, 4(1), 45-48.

  12. 12

    Zahidul Islam, Dilara Islam Sharif and Md. Aktar Hossain (2008), A Comparative Study of Azotobacter spp. from Different Soil Samples, Journal of Soil Nature, 2(3), 16-19.

II. Proceeding Papers:
  1. 13

    Moniruzzaman; Md. Zahidul Islam, Sabrina Sharmin, Hideo Dohra and Masahito Yamazaki, “Entry of Antimicrobial Peptide Lactoferricin B (4-9) into single vesicles and E. coli cells”, Proceedings of the 19th Takayanagi Kenjiro Memorial Symposium (November 21-22, 2017, Hamamatsu, Japan).

  2. 14

    Sabrina Sharmin, Zahidul Islam, Mohammad Abu Sayem Karal, Shibly Sayed Ul Alam, Hideo Dohra and Masahito Yamazaki, “Effects of mechanical property of lipid membranes on the entry of cell-penetrating peptide oligoarginine into a single vesicle”, Proceedings of the 18th Takayanagi Kenjiro Memorial Symposium (November 15-16, 2016, Hamamatsu, Japan).

  3. 15

    M Zahidul Islam, Sabrina Sharmin, and Masahito Yamazaki, “Effect of cholesterol on the entry of cell-penetrating peptide Transportan 10 (TP10) into a single vesicles”, Proceedings of the 17th Takayanagi Kenjiro Memorial Symposium (November 17-18, 2015, Hamamatsu, Japan), 29~33.

  4. 16

    M Zahidul Islam, HirotakaAriyama, Jahangir Md. Alam, and Masahito Yamazaki, “Visualization of entry of cell-penetrating peptide transportan 10 into a single vesicle by translocating across lipid membranes and its induced pores”, Proceedings of the 16th Takayanagi Kenjiro Memorial Symposium (November 11-12, 2014, Hamamatsu, Japan), PS1-3-1~5.

  5. 17

    Md. Alam, Md. Z. Islam, T. Tsuboi, Md. A. S. Karal, and M. Yamazaki, The Single GUV Method for Probing Elementary Processes of Peptide/Proteins-Induced Pore Formation in Biomembranes. Proceedings of the 15th Takayanagi Kenjiro Memorial Symposium (November 12-13, 2013, Hamamatsu, Japan), S7-4-1~5.

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    III. International Conference:

    1. Mizanur Rahman Moghal, Md. Zahidul Islam, Sabrina Sharmin, and Masahito Yamazaki, Continuous Detection of Entry of Cell-Penetrating Peptide Transportan 10 into Single Vesicles,” The 4th International symposium toward the future of advance researches in Shizuoka University 2018”, March 6, 2018, Shizuoka University, Hamamatsu Campus, Shizuoka, Japan.
    2. Zahidul Islam, Sabrina Sharmin, Victor Levadnyy, Sayed Ul Alam Shibly, and Masahito Yamazaki “Effects of mechanical property membrane on entry of cell-penetrating peptide into single vesicles” 19th International Union for Pure and Applied Biophysics Congress”, July 16-20, 2017, Edinburgh, United Kingdom (UK).
    3. Moniruzzaman; Md. Zahidul Islam, Sabrina Sharmin, Hideo Dohra, and Masahito Yamazaki “Entry of Lactoferricin B (4-9) into single vesicles and E. coli without damaging their membrane” 19th International Union for Pure and Applied Biophysics Congress”, July 16-20, 2017, Edinburgh, United Kingdom (UK).
    4. Zahidul Islam, Sabrina Sharmin, Victor Levadnyy, Sayed Ul Alam Shibly, and Masahito Yamazaki “The effect of tension on entry of CF-TP10 into single vesicle”. The 2017 international symposium toward the future of advance researches in Shizuoka University”, March 08, 2017, Shizuoka University, Hamamatsu, Shizuoka, Japan.
    5. Moniruzzaman; Md. Zahidul Islam, Hideo Dohra, and Masahito Yamazaki, “A mechanism of antimicrobial activity of a short peptide derived from Lactoferricin B” The 2017 international symposium toward the future of advance researches in Shizuoka University”, March 08, 2017, Shizuoka University, Hamamatsu, Shizuoka, Japan.
    6. Sabrina Sharmin, Zahidul Islam, Mohammad Abu Sayem Karal, Sayed Ul Alam Shibly, and Masahito Yamazaki, “Effect of lipid composition on the entry of cell-penetrating peptide oligoarginine (Rn) into single vesicles” The 2017 international symposium toward the future of advance researches in Shizuoka University”, February 27, 2017, Shizuoka University, Shizuoka, Japan.
    7. Sabrina Sharmin, Zahidul Islam, Masahito Yamazaki and Hideo Dohra “Effects of lipid composition on the entry of cell-penetrating peptide oligoarginine into single vesicles” The 61th Annual Meeting of the Biophysical Society, February 11–15, 2017, New Orleans, Louisiana, United States of America (USA).
    8. Sabrina Sharmin, Zahidul Islam, Mohammad Abu Sayem Karal, Shibly Sayed Ul Alam, Hideo Dohra, and Masahito Yamazaki “Effects of lipid composition on the entry of cell-penetrating peptide oligoarginine (Rn) into single vesicles” 6th Shizuoka University International Symposium 2016, December 08, 2016, Shizuoka University, Hamamatsu, Shizuoka, Japan.
    9. Zahidul Islam, Sabrina Sharmin, Victor Levadnyy, Sayed Ul Alam Shibly, and Masahito Yamazaki “Effects of membrane tension on entry of cell-penetrating peptide transportan 10 into single vesicles of lipid membranes” 1st International Symposium on Biomedical Engineering, by Ministry of Education, Culture, Sports, Science and Technology (MEXT), November 10-11, 2016, Tokyo Medical and Dental University, Tokyo, Japan.
    10. Sabrina Sharmin, Zahidul Islam, Mohammad Abu Sayem Karal, Shibly Sayed Ul Alam, Hideo Dohra, and Masahito Yamazaki “Effects of lipid composition on the entry of cell-penetrating peptide oligoarginine (Rn) into single vesicles” 1st International Symposium on Biomedical Engineering, by Ministry of Education, Culture, Sports, Science and Technology (MEXT), November 10-11, 2016, Tokyo Medical and Dental University, Tokyo, Japan.
    11. Md. Zahidul Islam, Ariyama, M. Jahangir Alam and M. Yamazaki “Entry of cell-penetrating peptide transportan 10 into a single vesicle by translocating across lipid membranes before pore formation”. The 2015 international symposium toward the future of advance researches in Shizuoka University”, January 27-28, 2015, Shizuoka University, Hamamatsu, Shizuoka, Japan.
    12. Md. Zahidul Islam, Hirotaka Ariyama, Md. Jahangir Alam and Masahito Yamazaki “Entry of cell-penetrating peptide transportan 10 into a single vesicle by translocating across lipid membranes and its induce pore”. The 2014 International Biophysics Congress”, August 3-7, 2014, Brisbane, Australia.

     IV. National Conference:

    1. Mizanur Rahman Moghal, Sabrina Sharmin, Masahito Yamazaki, and Md. Zahidul Islam, “Continuous Detection of Entry of Cell-Penetrating Peptide Transportan 10 into Single Vesicles,” H29 conference of cooperative research for biomedical engineering, March 9, 2018, Tokyo Institute of Technology, Tokyo, Japan.
    2. M Zahidul Islam, Sabrina Sharmin, Victor Levadnyy, Sayed Ul Alam Shibly, and Masahito Yamazaki “Thermal fluctuation of lipid bilayers affect the entry of cell-penetrating peptide Transportan 10 (TP10) into single vesicles” The 55th Annual Meeting of the Biophysical Society of Japan (BSJ2017), September 19-21, 2017, Kumamoto, Japan.
    3. Md Mizanur Moghal, Zahidul Islam, Sharmin Sabrina and Masahito Yamazaki “Effect of Membrane Potential on the Translocation of Cell-Penetrating Peptide Transportan 10 (TP10) across Lipid Bilayers” The 55th Annual Meeting of the Biophysical Society of Japan (BSJ2017), September 19-21, 2017, Kumamoto, Japan.
    4. Rajib Ahmed, Sayed Ul Alam Shibly, Zahidul Islam, and Masahito Yamazaki “Lateral Tension increases membrane permeability of water in lipid membranes” The 55th Annual Meeting of the Biophysical Society of Japan (BSJ2017), September 19-21, 2017, Kumamoto, Japan.
    5. Moniruzzaman; Md. Zahidul Islam, Sabrina Sharmin, Hideo Dohra, and Masahito Yamazaki “Entry of antimicrobial hexapeptide derived from Lactoferricin B into single cells of E. coli without damaging their membrane” The 55th Annual Meeting of the Biophysical Society of Japan (BSJ2017), September 19-21, 2017, Kumamoto, Japan.
    6. M Zahidul Islam, Sabrina Sharmin, Victor Levadnyy, Sayed Ul Alam Shibly, and Masahito Yamazaki “The mechanisms of translocation of cell-penetrating peptide transportan 10 into a single vesicle of lipid membranes.” BABG 1st National Congress 2017, April 28, 2017, Jahangirnagar University, Savar, Dhaka, Bangladesh.
    7. M Zahidul Islam, Sabrina Sharmin, and Masahito Yamazaki, “Mechanical properties of lipid bilayers affect the entry of cell-penetrating peptide transportan 10 into Single vesicles.” The 54th Annual Meeting of the Biophysical Society of Japan (BSJ2016), November 25-27, 2016, Tsukuba, Japan.
    8. Sabrina Sharmin, M Zahidul Islam, Mohammad Abu Sayem Karal, Sayed Ul Alam Shibly and Masahito Yamazaki, “Effects of lipid compositions on the entry of cell-penetrating peptide oligoarginine into single vesicles” The 54th Annual Meeting of the Biophysical Society of Japan (BSJ2016), November 25-27, 2016, Tsukuba, Japan.
    9. Moynul Hasan, Mohammad Abu Sayem Karal, Victor Levadnyy, M Zahidul Islam, and Masahito Yamazaki, “A mechanism of antimicrobial peptide, Magainin 2-induced pore formation in lipid membranes” The 54th Annual Meeting of the Biophysical Society of Japan (BSJ2016), November 25-27, 2016, Tsukuba, Japan.
    10. M Zahidul Islam, Sabrina Sharmin, and Masahito Yamazaki, “Effects of cholesterol on the entry of cell-penetrating peptide transportan 10 (TP10) into a single vesicle” The 53th Annual Meeting of the Biophysical Society of Japan (BSJ2015), September 13-15, 2015, Kanazawa, Japan.
    11. Sabrina Sharmin, M Zahidul Islam, and Masahito Yamazaki, “Investigation of the Entry of Cell-Penetrating Peptide, Poly-arginine into a Vesicle of Lipid Membrane Using the Single GUV Method” The 53th Annual Meeting of the Biophysical Society of Japan (BSJ2015), September 13-15, 2015, Kanazawa, Japan.
    12. M Zahidul Islam, Hirotaka Ariyama, Jahangir Md. Alam and Masahito Yamazaki “Entry of cell-penetrating peptide transportan 10 into a single vesicle by translocating across lipid membranes and its induced pores”. The 2015 workshop on Green Science and Technology of Global Young Researchers, January 26, 2015, Shizuoka University, Shizuoka, Japan.
    13. M Zahidul Islam, Hirotaka Ariyama, Jahangir Md. Alam and Masahito Yamazaki “Visualization of entry of cell-penetrating peptide transportan 10 into a single vesicle by translocating across lipid membranes and its induced pores”. The 16th Takayanagi Kenjiro Memorial Symposium, November 11-12, 2014, Shizuoka University, Hamamatsu, Shizuoka, Japan.
    14. Zahidul Islam, Ariyama Hirotaka, Jahangir Md. Alam and Yamazaki Masahito “The single GUV method reveals the translocation of cell-penetrating peptide transportan 10 across lipid membranes and its induced pores”. The 87th Annual Meeting of the Japanese Biochemical Society (JBS2014), October 15-18, 2014, Kyoto, Japan.
    15. Zahidul Islam, M. A. Sayem Karal, and Masahito Yamazaki “Effects of tension on entry of cell-penetrating peptide transportan 10 into a single vesicles and its pore formation in lipid membranesThe 52th Annual Meeting of the Biophysical Society of Japan (BSJ2014), September 25-27, 2014, Sapporo, Japan.
    16. Zahidul Islam, Hirotaka Ariyama, Md. Jahangir Alam, Masahito Yamazaki2 “Permeation of Cell-Penetrating Peptide Transportan 10 through Lipid Membranes before Pore Formation”. The 51st Annual Meeting of the Biophysical Society of Japan (BSJ51), October 28-30, 2013, Kyoto, Japan.
    17. A. Sayem Karal, Taka-aki Tsuboi, Md. Jahangir Alam, Md. Zahidul Islam, Masahito Yamazaki “Effects of Mechanical Properties of Lipid Membranes on Antimicrobial Peptide Magainin 2-Induced Pore Formation”. The 51st Annual Meeting of the Biophysical Society of Japan (BSJ51), October 28-30, 2013, Kyoto, Japan.

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