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- Dedicated to research and education for the breakthrough invention and advancement of life science technology from bench to clinic.
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BIOGRAPHY:
Dr. Md. Sharif Hossain is an Associate Professor at the Department of Biotechnology and Genetic Engineering, Faculty of Biological Sciences, Jahangirnagar University, Dhaka, Bangladesh. He is dedicated to research and education for the breakthrough invention and advancement of life science technology from bench to clinic.
After completing his secondary and tertiary level education from Bangladesh, he moved to Japan and achieved his M.Sc. and Ph.D. degree from the Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology in 2008 and 2011 respectively as MEXT (The Ministry of Education, Culture, Sports, Science and Technology, Japan) scholar. He was then awarded prestigious Postdoctoral Fellowship of Japan Society for the Promotion of Science (JSPS) and conducted cutting edge research at Frontier Research Centre, Tokyo Institute of Technology, Japan (2011~2013). In 2014, he joined as Senior Researcher at Biomaterials Centre for Regenerative Medical Engineering, Foundation for Advancement of International Science (FAIS), Tsukuba, Japan. By August 2014, he moved to Bangladesh and joined as an Assistant Professor at the Department of Biotechnology and Genetic Engineering, Jahangirnagar University. He also served as the chairman at the Department of Biotechnology and Genetic Engineering, Jahangirnagar University and successfully completed his tenure from July 2017 to July 2020.
Dr. Hossain’s research interest includes the field of nanobiotechnology, drug development, biomaterials design and regenerative medicine. He developed novel nonviral vector effective for cancer gene therapy and drug delivery. Moreover, he conducted cutting edge research to develop mammalian induced pluripotent stem (iPS) cell generation and guided differentiation for the regeneration of therapeutics cells. He also focused the influence of nano-biointerface on the intracellular regulation of stem cells (ES/iPS cells) for regenerative medicine and biomedical application. His current research focuses on the nanobiotechnology based approaches to overcome the challenges of antibiotic resistance. He has published more than 25 articles in peer reviewed international journals, 2 book chapters and 12 international conferences papers.
He was the recipients of MEXT scholarship (The Ministry of Education, Culture, Sports, Science and Technology, Japan) (2005~2011), Prestigious Fellowship of Japan Society for the Promotion of Science (JSPS) (2011~ 2013), Nucleic Acids Research Award (NAR Award) and Antisense (Kawahara) Award from Oligonucleotide Therapeutic Society, OTS (USA) (2009), Award of Excellence from Toin International Symposium on Biomedical Engineering, (Japan) (2007), Murakami Scholarship, Tokyo Institute of Technology, (Japan) (2008~ 2011), Bangladesh Education Leadership Award as Best Professor in Genetic Engineering Studies from World Education Congress (2019).
EDUCATION:
1995, Secondary School Certificate (SSC), Dawood Public School, Jessore, Bangladesh
1995 ~ 1997, Higher Secondary Certificate (HSC), Cantonment College, Jessore, Bangladesh
1998 ~ 2003, Bachelor of Science (BSc), Biotechnology and Genetic Engineering Discipline, Khulna University, Bangladesh
2005 ~ 2006, Research Student, Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Japan
2006 ~ 2008, Master of Engineering (MSc), Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Japan
2008 ~2011, Doctor of Engineering (PhD), Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Japan
2011/04/01~ 2011/08/31, Postdoctoral Fellow, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Japan
2011/09/01~ 2013/08/31, Foreign Researcher of Japan Society for the Promotion of Science (JSPS), Frontier Research Centre, Tokyo Institute of Technology, Japan
2013/09/01~ 2014/03/31, Scientific Research Fellow, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Japan
EMPLOYMENT
2014/04/01~ 2014/08/08, Senior Scientist, Biomaterials Centre for Regenerative Medical Engineering, Foundation for Advancement of International Science (FAIS), Tsukuba, JAPAN
2014/08/09~ 2017/01/30, Assistant Professor, Department of Biotechnology and Genetic Engineering, Jahangirnagar University, Dhaka-1342, BANGLADESH
2017/01/31~ Continuing : Associate Professor, Department of Biotechnology and Genetic Engineering, Jahangirnagar University, Dhaka-1342, BANGLADESH
RESEARCH HIGHLIGHTS
AWARDS & HONORS:
SOCIETY ACTIVITY:
LIST OF THE INTERNATIONAL SCIENTIFIC AND COLLABORATIVE MEETING ATTENDED
Bakul Akter, Ariful Islam Khan · Subarna Karmaker · Pollob Ghosh · Soma Saha · Shakil Ahmed Polash · Zinia Islam · Satya Ranjan Sarker · Md. Sharif Hossain · Hiroyuki Yasui · Tapan Kumar Saha, Chelation of zinc(II) with poly(γ‑glutamic acid) in aqueous solution: kinetics, binding constant, and its antimicrobial activity, Polymer Bulletin, https://doi.org/10.1007/s00289-020-03165-9 Received: 28 November 2019 / Revised: 2 March 2020 / Accepted: 10 March 2020, Impact Factor: 1.858
Saiful Islam, Md. Ahsanul Kabir, Md. Faizul Hossain Miraz, Effat Jahan Tamanna, Satya Ranjan Sarker, Zinia Islam, S. M. Jahangir Hossain, Sharif Hossain*, Gautam Kumar Deb* (* Corresponding Author), Investigation of Ovarian Follicular Waves and Major Hormonal Profile in Red Chittagong Cattle, Advances in Bioscience and Biotechnology, 2020, 11, 7- 2.
Hossain MM, Polash SA, Takikawa M, Shubhra RD, Saha T, Islam Z, Hossain S, Hasan MA, Takeoka S, Sarker SR, Investigation of the Antibacterial Activity and in vivo Cytotoxicity of Biogenic Silver Nanoparticles as Potent Therapeutics, Front Bioeng Biotechnol. 2019 Oct 9;7:239. Impact Factor: 5.122
Razib Datta Shubhra, Shakil Ahmed Polash, Tanushree Saha, Ashraful Hasan, Sharif Hossain, Zinia Islam*, Satya Ranjan Sarker* (* Corresponding Author), Investigation of the Phytoconstituents and Antioxidant Activity of Diospyros malabarica Fruit Extracts, Advances in Bioscience and Biotechnology, 2019, 10, 431-454.
Ratna Mondal, Shakil Ahmed Polash, Tanushree Saha, Zinia Islam, Md. Maniruzzaman Sikder, Nuhu Alam, Md. Sharif Hossain*, Satya Ranjan Sarker* (* Corresponding Author), Investigation of the Phytoconstituents and Bioactivity of Various Parts of Wild Type and Cultivated Phyllanthus emblica L., Advances in Bioscience and Biotechnology, 8, 211-227, 2017.
Shakil Ahmed Polash, Tanushree Saha, Md. Sharif Hossain and Satya Ranjan Sarker, Phytochemical contents, antioxidant and antibacterial activity of the ethanolic extracts of Centella asiatica (L.) Urb. leaf and stem, J U J. Biol. Sci., 2017 (June), 6(1): 51-57.
Shakil Ahmed Polash, Tanushree Saha, Md. Sharif Hossain, Satya Ranjan Sarker, Investigation of the Phytochemicals, Antioxidant, and Antimicrobial Activityof theAndrographispaniculata Leaf andStem Extracts, Advances in Bioscience and Biotechnology, 2017, 8, 149-162.
Adnan N, Mie M, Haque A, Hossain S, Mashimo Y, Akaike T, Kobatake E., Construction of a Defined Biomimetic Matrix for Long-Term Maintenance of Mouse Induced Pluripotent Stem Cells, ACS Bioconjug Chem., 27(7):1599-605, July 20, 2016. Impact Factor: 4.349
Haque A, Adnan N, Motazedian A, Akter F, Hossain S, Kutsuzawa K, Nag K, Kobatake E, Akaike T, An Engineered N-Cadherin Substrate for Differentiation, Survival, and Selection of Pluripotent Stem Cell-Derived Neural Progenitors, PLoS One, 10(8):e0135170, August 05, 2015. Impact Factor: 4.092
Wu X, Yamamoto H, Nakanishi H, Yamamoto Y, Inoue A, Tei M, Hirose H, Uemura M, Nishimura J, Hata T, Takemasa I, Mizushima T, Hossain S, Akaike T, Matsuura N, Doki Y, Mori M, Innovative delivery of siRNA to solid tumors by super carbonate apatite, PLoS One, 10(3):e0116022, March 04, 2015. Impact Factor: 4.092
Sharif Hossain, Ezharul Hoque Chowdhury, Nihad Adnan and Toshihiro Akaike, Chapter Title: Biocompatible apatite nano-particles: A versatile tool for cellular delivery of genes, siRNAs, Drugs and proteins, Book Title: Apatite: Synthesis, Structural Characterization and Biomedical Applications, Nova Publishers, USA, August 2014.
Juntaro Matsuzaki, Hidekazu Suzuki, Hitoshi Tsugawa, Mitsuhiro Watanabe, Sharif Hossain, Eri Arai, Yoshimasa Saito, Shigeki Sekine, Toshihiro Akaike, Yae Kanai, Ken-ichi Mukaisho, Johan Auwerx, Toshifumi Hibi, Bile Acids Increase Levels of microRNAs 221 and 222, Leading to Degradation of CDX2 During Esophageal Carcinogenesis, Gastroenterology, 145(6):1300-11, 2013 Dec. Impact Factor: 19.233
Hossain S, Yamamoto H, Chowdhury EH, Wu X, Hirose H, Haque A, Doki Y, Mori M, Akaike T, Fabrication and intracellular delivery of Doxorubicin/Carbonate Apatite Nanocomposites: Effiect on growth retardation of established Colon Tumor, PLoS One, 8(4):e60428, 2013. Impact Factor: 4.092
Hossain S*, Nag K*, (*equal contribution), Naznin S, Chowdhury EH, PKC activation promotes internalization of DNA-immobilized inorganic nano-crystals by clathrin-dependent endocytosis for efficient transgene expression in human lymphocytes, Journal of Nanomedicine and Nanotechnology, 4:174, 2013. Impact Factor: 3.57
Sharif Hossain, Ezharul Hoque Chowdhury and Toshihiro Akaike, Chapter Title: Inorganic Nanomaterials of Carbonate apatite as intracellular nucleic acid/drug transporters, Book Title: Bioengineered Nanomaterials, Taylor & Francis Publisher, CRC PRESS, USA. August 2013. (BOOK CHAPTER)
Stanislaus A, Bakhtiar A, Salleh D, Tiash S, Fatemian T, Hossain S, Akaike T, Chowdhury EH, Knockdown of PLC-gamma-2 and calmodulin 1 genes sensitizes human cervical adenocarcinoma cells to doxorubicin and paclitaxel, Cancer Cell Int., 12(1):30, 2012. Impact Factor: 3.618
Hossain S, Chowdhury EH, Akaike T, Nanoparticles and toxicity in therapeutic delivery: the ongoing debate, Therapeutic Deliv., 2(2): 125-132, 2011. (EDITORIAL)Impact Factor: 2.12
Haque A, Hexig B, Meng Q, Hossain S, Nagaoka M, Akaike T, The effect of recombinant E-cadherin substratum on the differentiation of endoderm-derived hepatocyte-like cells from embryonic stem cells, Biomaterials, 32(8): 2032-42, 2011. Impact Factor: 10.273
Hossain S, Stanislaus A, Chua MJ, Tada S, Tagawa Y, Chowdhury EH, Akaike T, Carbonate apatite-facilitated intracellularly delivered siRNA for efficient knockdown of functional genes, J. Control. Release, 147(1): 101-108, 2010. Impact Factor: 8.375
Hossain S, Tada S, Akaike T, Chowdhury EH, Influences of electrolytes and glucose on formulation of carbonate apatite nanocrystals for efficient gene delivery to mammalian cells, Anal. Biochem. 397: 156–161, 2010. Impact Factor: 2.507
Hossain S, Akaike T, Chowdhury EH, Current approaches for drug delivery to central nervous system, Curr. Drug Deliv., 7(5):389-397, 2010.Impact Factor: 1.709
Kutsuzawa K, Tada S, Hossain S, Akaike T, Chowdhury EH, Disrupting actin filaments promotes efficient transfection of a leukemia cell line using cell adhesive protein-embedded carbonate apatite particles, Anal. Biochem. 388: 164 -166, 2009. Impact Factor: 2.507
Sharif Hossain, Ezharul Hoque Chowdhury and Toshihiro Akaike. Efficient Delivery of siRNA by pH-Sensitive Inorganic Nanocrystals of Carbonate Apatite. Nucleic Acids Res., 37 (22): 7347-7348, 2009 Special editorial publication for award. Impact Factor: 11.147
Afrin,N., Sikder,M.M., Hossain,M.S. and Shilpi,R.Y., Bacillus cereus strain JUB1 16S ribosomal RNA gene, partial sequence, GenBank Accession of bacterial sequences, GenBank: MH552993.1, 2018.
Afrin,N., Sikder,M.M., Hossain,M.S. and Shilpi,R.Y., Bacillus cereus strain JUB2 16S ribosomal RNA gene, partial sequence, GenBank Accession of bacterial sequences, GenBank: MH552994.1, 2018.
Comments about my novel research: (from Editor in chief, Journal of Controlled Release) Park K. Carbonate apatite-facilitated intracellular delivery of siRNA. J Control Release. 147(1):1, 2010. Impact Factor: 8.375
Cover Story by Kinam Park
HOSSAIN, Biomaterials
Hossain, Editorial
Hossain, J Control Release
Sharif Hossain
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