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- Dedicated to research and education for the breakthrough invention and advancement of life science technology from bench to clinic.
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BIOGRAPHY:
Dr. Md. Sharif Hossain has been serving as a Professor at the Department of Biotechnology and Genetic Engineering, Faculty of Biological Sciences, Jahangirnagar University, Dhaka, Bangladesh. He is dedicated to research and education for the breakthrough invention and advancement of life science technology from bench to clinic.
After completing his secondary and tertiary level education from Bangladesh, he moved to Japan and achieved his M.Sc. and Ph.D. degree from the Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology in 2008 and 2011 respectively as MEXT (The Ministry of Education, Culture, Sports, Science and Technology, Japan) scholar. He was then awarded Postdoctoral Fellowship of Japan Society for the Promotion of Science (JSPS) and conducted cutting edge research at Frontier Research Centre, Tokyo Institute of Technology, Japan (2011~2013). In 2014, he joined as Researcher at Biomaterials Centre for Regenerative Medical Engineering, Foundation for Advancement of International Science (FAIS), Tsukuba, Japan. By August 2014, he moved to Bangladesh and joined as an Assistant Professor at the Department of Biotechnology and Genetic Engineering, Jahangirnagar University. He also served as the chairman at the Department of Biotechnology and Genetic Engineering, Jahangirnagar University and successfully completed his tenure from July 2017 to July 2020.
Dr. Hossain’s research interest includes the field of Nanobiotechnology, Regenerative Medicine, Gene Therapy and Drug Delivery, Stem Cell Biology, Biomedical Engineering, Biomaterials Design, Medical Biotechnology. He developed novel nonviral vector effective for cancer gene therapy and drug delivery. Moreover, he conducted cutting edge research to develop mammalian induced pluripotent stem (iPS) cell generation and guided differentiation for the regeneration of therapeutics cells. He also focused the influence of nano-biointerface on the intracellular regulation of stem cells (ES/iPS cells) for regenerative medicine and biomedical application. His current research focuses on the nanobiotechnology based approaches to overcome the challenges of antibiotic resistance. He has published more than 40 scientific articles including peer reviewed international journals, book chapters and international conferences papers.
He was the recipients of MEXT scholarship (The Ministry of Education, Culture, Sports, Science and Technology, Japan) (2005~2011), Fellowship of Japan Society for the Promotion of Science (JSPS) (2011~ 2013), Nucleic Acids Research Award (NAR Award) and Antisense (Kawahara) Award from Oligonucleotide Therapeutic Society, OTS (USA) (2009), Award of Excellence from Toin International Symposium on Biomedical Engineering, (Japan) (2007), Murakami Scholarship, Tokyo Institute of Technology, (Japan) (2008~ 2011), Bangladesh Education Leadership Award as Best Professor in Genetic Engineering Studies from World Education Congress (2019).
EDUCATION:
1995, Secondary School Certificate (SSC), Dawood Public School, Jessore, Bangladesh
1995 ~ 1997, Higher Secondary Certificate (HSC), Cantonment College, Jessore, Bangladesh
1998 ~ 2003, Bachelor of Science (BSc), Biotechnology and Genetic Engineering Discipline, Khulna University, Bangladesh
2005 ~ 2006, Research Student, Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Japan
2006 ~ 2008, Master of Engineering (MSc), Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Japan
2008 ~2011, Doctor of Engineering (PhD), Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Japan
2011/04/01~ 2011/08/31, Postdoctoral Fellow, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Japan
2011/09/01~ 2013/08/31, Foreign Researcher of Japan Society for the Promotion of Science (JSPS), Frontier Research Centre, Tokyo Institute of Technology, Japan
2013/09/01~ 2014/03/31, Scientific Research Fellow, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Japan
EMPLOYMENT
2014/04/01~ 2014/08/08, Researcher , Biomaterials Centre for Regenerative Medical Engineering, Foundation for Advancement of International Science (FAIS), Tsukuba, JAPAN
2014/08/09~ 2017/01/30, Assistant Professor, Department of Biotechnology and Genetic Engineering, Jahangirnagar University, Dhaka-1342, BANGLADESH
2017/01/31~ 2021/04/2o : Associate Professor, Department of Biotechnology and Genetic Engineering, Jahangirnagar University, Dhaka-1342, BANGLADESH
2021/04/21~ Continuing : Professor, Department of Biotechnology and Genetic Engineering, Jahangirnagar University, Dhaka-1342, BANGLADESH
RESEARCH HIGHLIGHTS
AWARDS & HONORS:
SOCIETY ACTIVITY:
LIST OF THE INTERNATIONAL SCIENTIFIC AND COLLABORATIVE MEETING ATTENDED
Nihad Adnan, Md. Ahsanul Haq, Salma Akter. M. Shafiul Alam Sajal, Md. Fokhrul Islam, Taslin Jahan Mou, Mohd. Raeed Jamiruddin, Fatema Tuz Jubyda, Md. Salequl Islam, Jamsheda Ferdous Tuli, Syeda Moriam Liza, Sharif Hossain, Zinia Islam, Sohel Ahmed, Shahad Saif Khandker, Rubel Hossain, Md. Firoz Ahmed, Mohib Ullah Khondoker, Nafisa Azmuda, Md. Anowar Khasru Parvez, Antibody Response after Homologous and Heterologous Prime–Boost COVID-19 Vaccination in a Bangladeshi Residential University Cohort,Vaccines 2024, 12(5), 482; https://doi.org/10.3390/vaccines12050482 Impact Factor 7.8
Shanaz Fatema Bristy, Md. Reaz Uddin, Nowshin Jahan, Dewan Zubaer Islam, Bushra Ayat Meghla, Taslima Akter Tisha, Md. Aftab Uddin, Mohammad Tarequl Islam, Masayasu Mie, Eiry Kobatake, Mohib Ullah Khondoker, Taslin Jahan Mou, Md. Ahsanul Haq, Md. Fokhrul Islam, Zinia Islam, Md. Sharif Hossain, Nafisa Azmuda, Mohd. Raeed Jamiruddin, Susmita Sinha, Mainul Haque, Nihad Adnan, Misdiagnosis of Bacterial Pathogens by the Diagnostic Centers: A Potential Route for Antibiotic Resistance, Journal of Applied Pharmaceutical Science,p 001-011, Dec 14, 2023. DOI: 10.7324/JAPS.2024.175488 (Scopus Indexed)
Chironjit Kumar Shaha, Bithy Sarker, Shurid Kishore Mahalanobish, Md. Sharif Hossain, Subarna Karmaker, and Tapan Kumar Saha Kinetics, Equilibrium, and Thermodynamics for Conjugation of Chitosan with Insulin-Mimetic [meso-Tetrakis(4-sulfonatophenyl)porphyrinato] oxovanadate (IV)(4−) in an Aqueous Solution, ACS Omega, October 2023 DOI: 10.1021/acsomega.3c05804 Impact Factor 4.1
Israt Jahan Jhumi, Tusher-Al- Arafat, Polash Chandra Karmakar , Md. Arifuzzaman, Md. Sharif Hossain, Naznin Akhtar, S. M. Asaduzzaman, Silver Nanoparticle Incorporated Human Amniotic Membrane Gel Accelerates Second-Degree BurnWound Healing inWister Rat, Evidence-Based Complementary and Alternative Medicine, Volume 2023, p1-15, https://doi.org/10.1155/2023/9808556, Impact Factor 2.65
Naznin Jahan, Tanvir Ahamed, Arun Das, Md. Arif Khan, Sharif Hossain, Satya Ranjan Sarker and Mohammad Mahfuz Ali khan Shawan, In Silico Subtractive Genomics Approach Characterizes a Hypothetical Protein (MG_476) from Microplasma Genitalium G37, Journal of Clinincal and Experimental Investigations, 13, 3, pp.1-10, 2022. doi: https://doi.org/10.29333/jcei/12377
Md. Sabbir Ahmmed, Md. Maniruzzaman Sikder, Satya Ranjan Sarker, Md. Sharif Hossain, Razib Datta Shubhra, Nuhu Alam, First Report of Pseudopestalotiopsis theae Causing Aloe vera Leaf Spot Disease in Bangladesh, American Journal of Plant Sciences, Vol.13 No.2, February 18, 2022, Impact Factor 1.17
Razib Datta Shubhra, Shakil Ahmed Polash, Md. Monir Hossain, Amir Hamza, Md. Mehedi Hasan Tushar, Tanushree Saha, Md. Ashraful Hasan, Md. Maniruzzaman Sikder,Nuhu Alam, Zinia Islam , Md. Sharif Hossain, Satya Ranjan Sarker, Investigation of the Antimicrobial Activity and in Vivo Cytotoxicity of Diospyros malabarica (Desr.) Kostel. Fruit Extracts, Natural Science Vol.13 No.8,August 3, 2021, Impact Factor 2.3
Bakul Akter, Ariful Islam Khan · Subarna Karmaker · Pollob Ghosh · Soma Saha · Shakil Ahmed Polash · Zinia Islam · Satya Ranjan Sarker · Md. Sharif Hossain · Hiroyuki Yasui · Tapan Kumar Saha, Chelation of zinc(II) with poly(γ‑glutamic acid) in aqueous solution: kinetics, binding constant, and its antimicrobial activity, Polymer Bulletin, https://doi.org/10.1007/s00289-020-03165-9 Received: 28 November 2019 / Revised: 2 March 2020 / Accepted: 10 March 2020, Impact Factor: 2.84
Saiful Islam, Md. Ahsanul Kabir, Md. Faizul Hossain Miraz, Effat Jahan Tamanna, Satya Ranjan Sarker, Zinia Islam, S. M. Jahangir Hossain, Sharif Hossain*, Gautam Kumar Deb* (* Corresponding Author), Investigation of Ovarian Follicular Waves and Major Hormonal Profile in Red Chittagong Cattle, Advances in Bioscience and Biotechnology, 2020, 11, 7- 2.
Hossain MM, Polash SA, Takikawa M, Shubhra RD, Saha T, Islam Z, Hossain S, Hasan MA, Takeoka S, Sarker SR, Investigation of the Antibacterial Activity and in vivo Cytotoxicity of Biogenic Silver Nanoparticles as Potent Therapeutics, Front Bioeng Biotechnol. 2019 Oct 9;7:239. Impact Factor: 6.064
Razib Datta Shubhra, Shakil Ahmed Polash, Tanushree Saha, Ashraful Hasan, Sharif Hossain, Zinia Islam*, Satya Ranjan Sarker* (* Corresponding Author), Investigation of the Phytoconstituents and Antioxidant Activity of Diospyros malabarica Fruit Extracts, Advances in Bioscience and Biotechnology, 2019, 10, 431-454.
Ratna Mondal, Shakil Ahmed Polash, Tanushree Saha, Zinia Islam, Md. Maniruzzaman Sikder, Nuhu Alam, Md. Sharif Hossain*, Satya Ranjan Sarker* (* Corresponding Author), Investigation of the Phytoconstituents and Bioactivity of Various Parts of Wild Type and Cultivated Phyllanthus emblica L., Advances in Bioscience and Biotechnology, 8, 211-227, 2017.
Shakil Ahmed Polash, Tanushree Saha, Md. Sharif Hossain and Satya Ranjan Sarker, Phytochemical contents, antioxidant and antibacterial activity of the ethanolic extracts of Centella asiatica (L.) Urb. leaf and stem, J U J. Biol. Sci., 2017 (June), 6(1): 51-57.
Adnan N, Mie M, Haque A, Hossain S, Mashimo Y, Akaike T, Kobatake E., Construction of a Defined Biomimetic Matrix for Long-Term Maintenance of Mouse Induced Pluripotent Stem Cells, ACS Bioconjug Chem., 27(7):1599-605, July 20, 2016. Impact Factor: 6.069
Haque A, Adnan N, Motazedian A, Akter F, Hossain S, Kutsuzawa K, Nag K, Kobatake E, Akaike T, An Engineered N-Cadherin Substrate for Differentiation, Survival, and Selection of Pluripotent Stem Cell-Derived Neural Progenitors, PLoS One, 10(8):e0135170, August 05, 2015. Impact Factor: 4.092
Wu X, Yamamoto H, Nakanishi H, Yamamoto Y, Inoue A, Tei M, Hirose H, Uemura M, Nishimura J, Hata T, Takemasa I, Mizushima T, Hossain S, Akaike T, Matsuura N, Doki Y, Mori M, Innovative delivery of siRNA to solid tumors by super carbonate apatite, PLoS One, 10(3):e0116022, March 04, 2015. Impact Factor: 4.092
Sharif Hossain, Ezharul Hoque Chowdhury, Nihad Adnan and Toshihiro Akaike, Chapter Title: Biocompatible apatite nano-particles: A versatile tool for cellular delivery of genes, siRNAs, Drugs and proteins, Book Title: Apatite: Synthesis, Structural Characterization and Biomedical Applications, Nova Publishers, USA, August 2014.
Juntaro Matsuzaki, Hidekazu Suzuki, Hitoshi Tsugawa, Mitsuhiro Watanabe, Sharif Hossain, Eri Arai, Yoshimasa Saito, Shigeki Sekine, Toshihiro Akaike, Yae Kanai, Ken-ichi Mukaisho, Johan Auwerx, Toshifumi Hibi, Bile Acids Increase Levels of microRNAs 221 and 222, Leading to Degradation of CDX2 During Esophageal Carcinogenesis, Gastroenterology, 145(6):1300-11, 2013 Dec. Impact Factor: 33.88
Hossain S, Yamamoto H, Chowdhury EH, Wu X, Hirose H, Haque A, Doki Y, Mori M, Akaike T, Fabrication and intracellular delivery of Doxorubicin/Carbonate Apatite Nanocomposites: Effiect on growth retardation of established Colon Tumor, PLoS One, 8(4):e60428, 2013. Impact Factor: 4.092
Hossain S*, Nag K*, (*equal contribution), Naznin S, Chowdhury EH, PKC activation promotes internalization of DNA-immobilized inorganic nano-crystals by clathrin-dependent endocytosis for efficient transgene expression in human lymphocytes, Journal of Nanomedicine and Nanotechnology, 4:174, 2013. Impact Factor: 3.57
Sharif Hossain, Ezharul Hoque Chowdhury and Toshihiro Akaike, Chapter Title: Inorganic Nanomaterials of Carbonate apatite as intracellular nucleic acid/drug transporters, Book Title: Bioengineered Nanomaterials, Taylor & Francis Publisher, CRC PRESS, USA. August 2013. (BOOK CHAPTER)
Stanislaus A, Bakhtiar A, Salleh D, Tiash S, Fatemian T, Hossain S, Akaike T, Chowdhury EH, Knockdown of PLC-gamma-2 and calmodulin 1 genes sensitizes human cervical adenocarcinoma cells to doxorubicin and paclitaxel, Cancer Cell Int., 12(1):30, 2012. Impact Factor: 5.99
Hossain S, Chowdhury EH, Akaike T, Nanoparticles and toxicity in therapeutic delivery: the ongoing debate, Therapeutic Deliv., 2(2): 125-132, 2011. (EDITORIAL)Impact Factor: 2.12
Haque A, Hexig B, Meng Q, Hossain S, Nagaoka M, Akaike T, The effect of recombinant E-cadherin substratum on the differentiation of endoderm-derived hepatocyte-like cells from embryonic stem cells, Biomaterials, 32(8): 2032-42, 2011. Impact Factor: 15.30
Hossain S, Stanislaus A, Chua MJ, Tada S, Tagawa Y, Chowdhury EH, Akaike T, Carbonate apatite-facilitated intracellularly delivered siRNA for efficient knockdown of functional genes, J. Control. Release, 147(1): 101-108, 2010. Impact Factor: 11.46
Hossain S, Tada S, Akaike T, Chowdhury EH, Influences of electrolytes and glucose on formulation of carbonate apatite nanocrystals for efficient gene delivery to mammalian cells, Anal. Biochem. 397: 156–161, 2010. Impact Factor: 3.19
Hossain S, Akaike T, Chowdhury EH, Current approaches for drug delivery to central nervous system, Curr. Drug Deliv., 7(5):389-397, 2010.Impact Factor: 3.75
Kutsuzawa K, Tada S, Hossain S, Akaike T, Chowdhury EH, Disrupting actin filaments promotes efficient transfection of a leukemia cell line using cell adhesive protein-embedded carbonate apatite particles, Anal. Biochem. 388: 164 -166, 2009. Impact Factor: 3.19
Sharif Hossain, Ezharul Hoque Chowdhury and Toshihiro Akaike. Efficient Delivery of siRNA by pH-Sensitive Inorganic Nanocrystals of Carbonate Apatite. Nucleic Acids Res., 37 (22): 7347-7348, 2009 Special editorial publication for award. Impact Factor: 19.16
Afrin,N., Sikder,M.M., Hossain,M.S. and Shilpi,R.Y., Bacillus cereus strain JUB1 16S ribosomal RNA gene, partial sequence, GenBank Accession of bacterial sequences, GenBank: MH552993.1, 2018.
Afrin,N., Sikder,M.M., Hossain,M.S. and Shilpi,R.Y., Bacillus cereus strain JUB2 16S ribosomal RNA gene, partial sequence, GenBank Accession of bacterial sequences, GenBank: MH552994.1, 2018.
Comments about my novel research: (from Editor in chief, Journal of Controlled Release) Park K. Carbonate apatite-facilitated intracellular delivery of siRNA. J Control Release. 147(1):1, 2010. Impact Factor: 11.46
Cover Story by Kinam Park
HOSSAIN, Biomaterials
Hossain, Editorial
Hossain, J Control Release
Sharif Hossain
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